MARK1/2/3/4(Phospho Thr215) Polyclonal Antibody

SKU: BT-AP11126

Size:100μL

Background:Catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,enzyme regulation:Activated by phosphorylation on Thr-215 by STK11 in complex with STE20-related adapter-alpha (STRAD alpha) pseudo kinase and CAB39.,May play a role in cytoskeletal stability.,Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. MARK subfamily.,Contains 1 KA1 (kinase-associated) domain.,Contains 1 protein kinase domain.,Contains 1 UBA domain.,subcellular location:Appears to localize to an intracellular network.,tissue specificity:Highly expressed in heart, skeletal muscle, brain, fetal brain and fetal kidney.,

Research_area:Signal transduction

Target_protein:MARK1/2/3/4

applications:IHC-p, IF, ELISA

Reactivity:Human, Mouse, Rat

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:Serine/threonine-protein kinase MARK1/2/3/4

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):89003

UniProt accession:Human: Q9P0L2/Q7KZI7/P27448/Q96L34; Rat: O08678/O08679/Q8VHF0

Synonyms:Serine/threonine-protein kinase MARK1/2/3/4; MARK1; KIAA1477; MARK; Serine/threonine-protein kinase MARK1; MAP/microtubule affinity-regulating kinase 1; PAR1 homolog c; Par-1c; Par1c; MARK2; EMK1; Serine/threonine-protein kinase MARK2; ELKL motif kinase 1; EMK-1; MAP/microtubule affin

GeneID:Human: 4139/2011/4140/57787; Mouse: 226778/13728/17169/232944; Rat: 117016/60328/170577