MAGEC2 Antibody - Cat. #: CSB-PA574003

SKU: CSB-PA574003

Size :100ul

Clone Number:

Aliases:Cancer testis antigen 10 antibody; Cancer/testis antigen 10 antibody; CT10 antibody; HCA587 antibody; Hepatocellular cancer antigen 587 antibody; Hepatocellular carcinoma associated antigen 587 antibody; Hepatocellular carcinoma-associated antigen 587 antibody; MAGC2_HUMAN antibody; MAGE C2 antigen antibody; MAGE E1 antigen antibody; MAGE family member C2 antibody; MAGE-C2 antigen antibody; MAGE-E1 antigen antibody; MAGEC2 antibody; Melanoma antigen family C 2 antibody; Melanoma antigen family C2 antibody; Melanoma antigen family E 1 cancer/testis specific antibody; Melanoma associated antigen C2 antibody; Melanoma-associated antigen C2 antibody; MGC13377 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q9UBF1

Immunogen:Synthesized peptide derived from internal of Human MAGEC2.

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, WB; WB:1:500-1:3000

Background:Proposed to enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. In vitro enhances ubiquitin ligase activity of TRIM28 and stimulates p53/TP53 ubiquitination in presence of Ubl-conjugating enzyme UBE2H leading to p53/TP53 degradation. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzymes (E2) at the E3:substrate complex.

Gure A.O., Int. J. Cancer 85:726-732(2000) [PubMed: 10699956].
Lucas S., Int. J. Cancer 87:55-60(2000) [PubMed: 10861452].
Wang Y., J. Immunol. 169:1102-1109(2002) [PubMed: 12097419].

Clonality:Polyclonal

Isotype:IgG

Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:MAGEC2

Research Areas:Cancer;Immunology