MAFA Polyclonal Antibody

SKU: E-AB-53394

Size::120μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Polyclonal Antibodies

Abbreviation:MAFA

Target Synonym:HMafA;Mafa;MAFA;Pancreatic beta cell specific transcriptional activator;Pancreatic beta-cell-specific transcriptional activator;RIPE3b1;Transcription factor MafA;Transcription factor RIPE3b1;v maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian);v maf musculoaponeurotic fibrosarcoma oncogene homolog A;V-maf musculoaponeurotic fibrosarcoma oncogene homolog A

Research Areas:Cancer;Epigenetics and Nuclear Signaling;Signal transduction

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse

Application:WB

Isotype:IgG

Clonality:Polyclonal

Clone NO.:

UNIProt ID:Q8NHW3

Accession:

Background:Members of the Maf family of basic region/leucine zipper (bZIP) transcription factors affect transcription in either a positive or negative fashion, depending on their particular protein partner and the context of the target promoter. c-Maf (Maf-2) and the closely related family members.MAFA acts as a transcriptional factor. Specifically binds the insulin enhancer element RIPE3b and activates insulin gene expression. Cooperates synergistically with NEUROD1 and PDX1. Phosphorylation by GSK3 increases its transcriptional activity and is required for its oncogenic activity.

Concentration:1.2 mg/mL

Immunogen:Synthetic peptide of human MAFA

Buffer:PBS with 0.05% NaN3 and 40% Glycerol,pH7.4

Purification method:Antigen affinity purification

Dilution:WB 1:500-1:2000

Calculated MW:37 kDa

ObservedMW:Refer to figures