LysRS Monoclonal Antibody

SKU: BT-MCA0858

Size:100μL

Background:Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. Lysyl-tRNA synthetase is a homodimer localized to the cytoplasm which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Research_area:Epigenetics and nuclear signaling

Target_protein:KARS

applications:WB, IHC-p, IF, ELISA

Reactivity:Human

Clonality:Monoclonal

Clone ID:

Host:Mouse

Isotype:IgG

Gene Symbol/ Name:Lysyl-tRNA synthetase

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):N/A

UniProt accession:Human: Q15046; Mouse: Q99MN1

Synonyms:KARS; KIAA0070; Lysine--tRNA ligase; Lysyl-tRNA synthetase; LysRS

GeneID:Human: 3735