LTOR3 rabbit pAb

SKU: ES10562

Size: 100μL

Source:Rabbit

Applications:WB;ELISA

Reactivity:Human;Mouse;Rat

Dilution:WB 1:500-2000 ELISA 1:5000-20000

Immunogen:Synthesized peptide derived from human protein . at AA range: 30-110

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:1 mg/ml

Observed_band(KD):13kD

Human_gene_id:8649

Human_swiss_prot_no:Q9UHA4

Subcellular_location:Late endosome membrane ; Peripheral membrane protein ; Cytoplasmic side .

Other_name:

Background:This gene encodes a scaffold protein that functions in the extracellular signal-regulated kinase (ERK) cascade. The protein is localized to late endosomes by the mitogen-activated protein-binding protein-interacting protein, and binds specifically to MAP kinase kinase MAP2K1/MEK1, MAP kinase MAPK3/ERK1, and MAP kinase MAPK1/ERK2. Studies of the orthologous gene in mouse indicate that it regulates late endosomal traffic and cell proliferation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome 13. [provided by RefSeq, Aug 2011],