LPA Monoclonal Antibody

SKU: BT-MCA4510

Size:100μL

Background:LPA: lipoprotein, Lp(a). Apo(a) is the main constituent of lipoprotein(a) (lp(a)). It has serine proteinase activity and is able of autoproteolysis. Inhibits tissue-type plasminogen activator 1.Lp(a) may be a ligand for megalin/gp 330.Apo(a) is known to be proteolytically cleaved, leading to the formation of the so-called mini-lp(a).Apo(a) fragments accumulate in atherosclerotic lesions,where they may promote thrombogenesis.O-glycosylation may limit the extent of proteolytic fragmentation.

Research_area:Cancer, Signal transduction, Metabolism, Cardiovascular

Target_protein:LPA

applications:IHC

Reactivity:Human

Clonality:Monoclonal

Clone ID:8F6A9

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:LPA

Immunogen:Purified recombinant fragment of LPA (4330-4521) expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Ascitic fluid containing 0.03% sodium azide.

Concentration:

Molecular weight(Da):

UniProt accession:P08519

Synonyms:LP, AK38, APOA, LPA

GeneID:4018