LOXL4 Rabbit Polyclonal Antibody

SKU: BT-AP11100

Size:100μL

Background:This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue| encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity| suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation| senescence| tumor suppression| cell growth control| and chemotaxis to each member of the family.

Research_area:Cancer; Signal transduction

Target_protein:LOXL4

applications:WB

Reactivity:Human, Mouse

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:LOXL4

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):83160

UniProt accession:Human: Q96JB6; Mouse: Q924C6

Synonyms:LOXL4

GeneID:Human: 84171; Mouse: 67573