LILRB1 Antibody, FITC conjugated - Cat. #: CSB-PA847747LC01HU

SKU: CSB-PA847747LC01HU

Size :50ug

Clone Number:

Aliases:CD85 antibody; CD85 antigen antibody; CD85 antigen like family member J antibody; CD85 antigen-like family member J antibody; CD85j antibody; CD85j antigen antibody; Ig like transcript 2 antibody; ILT 2 antibody; ILT-2 antibody; ILT2 antibody; immunoglobulin like transcript 2 antibody; Immunoglobulin-like transcript 2 antibody; leukocyte Ig like receptor 1 antibody; Leukocyte immunoglobulin like receptor 1 antibody; leukocyte immunoglobulin like receptor subfamily B member 1 antibody; Leukocyte immunoglobulin like receptor subfamily B member 1 precursor antibody; leukocyte immunoglobulin like receptor subfamily B member 1 soluble isoform antibody; leukocyte immunoglobulin like receptor, subfamily B, member 1 antibody; Leukocyte immunoglobulin-like receptor 1 antibody; Leukocyte immunoglobulin-like receptor subfamily B member 1 antibody; leukocyte immunoglobulin-like receptor subfamily B member 1 soluble isoform antibody; leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1 antibody; LILRB1 antibody; LIR 1 antibody; LIR-1 antibody; LIR1 antibody; LIRB1_HUMAN antibody; MIR 7 antibody; MIR-7 antibody; MIR7 antibody; Monocyte/macrophage immunoglobulin like receptor 7 antibody; Monocyte/macrophage immunoglobulin-like receptor 7 antibody; PIR B antibody; PIRB antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q8NHL6

Immunogen:Recombinant Human Leukocyte immunoglobulin-like receptor subfamily B member 1 protein (483-650AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:

Background:Receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles. Receptor for H301/UL18, a human cytomegalovirus class I MHC homolog. Ligand binding results in inhibitory signals and down-regulation of the immune response. Engagement of LILRB1 present on natural killer cells or T-cells by class I MHC molecules protects the target cells from lysis. Interaction with HLA-B or HLA-E leads to inhibition of the signal triggered by FCER1A and inhibits serotonin release. Inhibits FCGR1A-mediated phosphorylation of cellular proteins and mobilization of intracellular calcium ions.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:FITC

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:LILRB1

Research Areas:Immunology