LDLR Polyclonal Antibody

SKU: E-AB-70239

Size::120μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Polyclonal Antibodies

Abbreviation:LDLR

Target Synonym:FH;FHC;LDL R;LDL receptor;LDLCQ2;Ldlr;LDLR;Low Density Lipoprotein Receptor;Low density lipoprotein receptor class A domain containing protein 3;Low density lipoprotein receptor familial hypercholesterolemia;Low-density lipoprotein receptor

Research Areas:Cancer;Cardiovascular;Metabolism;Signal Transduction

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:IHC

Isotype:IgG

Clonality:Polyclonal

Clone NO.:

UNIProt ID:P01130,P35951,P35952

Accession:

Background:LDLR (low density lipoprotein receptor) is a member of the LDL receptor gene family and is involved in receptor-mediated endocytosis of specific ligands. The LDLR is a cell surface glycoprotein that scavenges LDL from the blood and regulates plasma LDL cholesterol. The cytoplasmic domain of the LDL receptor is necessary for the receptor to cluster in coated pits,which promotes the rapid endocytosis of bound LDL. The protein is highly glycosylated through N- and O-linkages and thus migrates at 100 to 160 kDa bands on SDS-PAGE.

Concentration:1 mg/mL

Immunogen:KLH conjugated Synthetic peptide corresponding to LDL Receptor

Buffer:PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4

Purification method:Affinity purification

Dilution:IHC 1:200-1:1000

Calculated MW:

ObservedMW: