LAMTOR3 Antibody - Cat. #: CSB-PA013477ESR2HU

SKU: CSB-PA013477ESR2HU

Size :50ul

Clone Number:

Aliases:LAMTOR3 antibody; Late endosomal/lysosomal adaptor and MAPK and MTOR activator 3 antibody; LTOR3_HUMAN antibody; MAP2K1IP1 antibody; MEK binding partner 1 antibody; MEK partner 1 antibody; MEK-binding partner 1 antibody; Mitogen activated protein kinase kinase 1 interacting protein 1 antibody; Mitogen-activated protein kinase kinase 1-interacting protein 1 antibody; Mitogen-activated protein kinase scaffold protein 1 antibody; Mp1 antibody; Ragulator complex protein LAMTOR3 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q9UHA4

Immunogen:Recombinant Human Ragulator complex protein LAMTOR3 protein (1-124AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background:As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the lysosomal V-ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag. Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. Adapter protein that enhances the efficiency of the MAP kinase cascade facilitating the activation of MAPK2.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen Affinity Purified

Conjugate:Non-conjugated

Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:LAMTOR3

Research Areas:Signal transduction