KMT5B Antibody, Biotin conjugated - Cat. #: CSB-PA674569LD01HU

SKU: CSB-PA674569LD01HU

Size :50ug

Clone Number:

Aliases:CGI 85 antibody; CGI85 antibody; Histone-lysine N-methyltransferase KMT5B antibody; Kmt5b antibody; KMT5B_HUMAN antibody; Lysine N-methyltransferase 5B antibody; Lysine-specific methyltransferase 5B antibody; MGC118906 antibody; MGC118909 antibody; MGC21161 antibody; MGC703 antibody; Su(var)4-20 homolog 1 antibody; Suppressor of variegation 4 20 homolog 1 antibody; Suppressor of variegation 4-20 homolog 1 antibody; Suv4-20h1 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q4FZB7

Immunogen:Recombinant Human Histone-lysine N-methyltransferase KMT5B protein (100-150AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA

Background:Histone methyltransferase that specifically trimethylates \'Lys-20\' of histone H4. H4 \'Lys-20\' trimethylation represents a specific tag for epigenetic transcriptional repression. Mainly functions in pericentric heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin in these regions. KMT5B is targeted to histone H3 via its interaction with RB1 family proteins (RB1, RBL1 and RBL2) (By similarity). Plays a role in myogenesis by regulating the expression of target genes, such as EID3.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:Biotin

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:KMT5B

Research Areas:Epigenetics and Nuclear Signaling; Signal transduction