KHDRBS2 Monoclonal Antibody

SKU: BT-MCA2828

Size:100μL

Background:RNA-binding protein that plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. Its phosphorylation by FYN inhibits its ability to regulate splice site selection. Induces an increased concentration-dependent incorporation of exon in CD44 pre-mRNA by direct binding to purine-rich exonic enhancer. May function as an adapter protein for Src kinases during mitosis. Binds both poly(A) and poly(U) homopolymers. Phosphorylation by PTK6 inhibits its RNA-binding ability (By similarity)

Research_area:Epigenetics and nuclear signaling

Target_protein:KHDRBS2

applications:WB, FCM

Reactivity:Human, Mouse

Clonality:Monoclonal

Clone ID:3D12C11

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:KHDRBS2

Immunogen:Purified recombinant fragment of human KHDRBS2 (AA: 160-349) expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Purified antibody in PBS with 0.05% sodium azide.

Concentration:

Molecular weight(Da):39kDa

UniProt accession:Q5VWX1

Synonyms:SLM1, SLM-1, bA535F17.1

GeneID:202559