KDM3B Polyclonal Antibody

SKU: BT-AP10662

Size:100μL

Background:cofactor:Binds 1 Fe(2+) ion per subunit.,Leu-Xaa-Xaa-Leu-Leu (LXXLL) motifs are known to mediate the association with nuclear receptors.,Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate. May have tumor suppressor activity.,miscellaneous:Its gene is located in the 5q region of the genome which is deleted in del(5q) interstitial deletion, a frequent deletion found in myeloid leukemias and myelodysplasias, suggesting that it may be a good candidate for the del(5q) tumor suppressor gene.,Belongs to the JHDM2 histone demethylase family.,Contains 1 JmjC domain.,tissue specificity:Ubiquitous. Highly expressed in placenta, skeletal muscle, kidney, heart and liver.,

Research_area:Cancer; Epigenetics and nuclear signaling

Target_protein:KDM3B

applications:WB, ELISA

Reactivity:Human, Mouse

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:Lysine-specific demethylase 3B

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):

UniProt accession:Human: Q7LBC6; Mouse: Q6ZPY7

Synonyms:Lysine-specific demethylase 3B ;EC 1.14.11.-;JmjC domain-containing histone demethylation protein 2B;Jumonji domain-containing protein 1B;Nuclear protein 5qNCA

GeneID:Human: 51780