KCNQ1 Antibody - Cat. #: CSB-PA942745

SKU: CSB-PA942745

Size :50ul

Clone Number:

Aliases:ATFB1 antibody; ATFB3 antibody; FLJ26167 antibody; IKs producing slow voltage-gated potassium channel subunit alpha antibody; IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1 antibody; Jervell and Lange-Nielsen syndrome 1 antibody; JLNS1 antibody; KCNA8 antibody; KCNA9 antibody; KCNQ1 antibody; KCNQ1_HUMAN antibody; kidney and cardiac voltage dependend K+ channel antibody; KQT-like 1 antibody; Kv1.9 antibody; Kv7.1 antibody; KVLQT1 antibody; long (electrocardiographic) QT syndrome, Ward-Romano syndrome 1 antibody; LQT antibody; LQT1 antibody; Potassium channel, voltage-gated, shaker-relatd subfamily, member 9 antibody; Potassium voltage-gated channel subfamily KQT member 1 antibody; potassium voltage-gated channel, KQT-like subfamily, member 1 antibody; RWS antibody; slow delayed rectifier channel subunit antibody; SQT2 antibody; Voltage-gated potassium channel subunit Kv7.1 antibody; WRS antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P51787

Immunogen:Fusion protein of Human KCNQ1

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, WB, IHC; ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:50-1:200

Background:This gene encodes a voltage-gated potassium channel required for repolarization phase of the cardiac action potential. This protein can form heteromultimers with two other potassium channel proteins, KCNE1 and KCNE3. Mutations in this gene are associated with hereditary long QT syndrome 1 (also known as Romano-Ward syndrome), Jervell and Lange-Nielsen syndrome, and familial atrial fibrillation. This gene exhibits tissue-specific imprinting, with preferential expression from the maternal allele in some tissues, and biallelic expression in others. This gene is located in a region of chromosome 11 amongst other imprinted genes that are associated with Beckwith-Wiedemann syndrome (BWS), and itself has been shown to be disrupted by chromosomal rearrangements in patients with BWS. Alternatively spliced transcript variants have been found for this gene.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:KCNQ1

Research Areas:Neuroscience;Cardiovascular;Metabolism;Signal transduction