KCNN4 antibody , Cat. # FNab04499

SKU: FNab04499

Size:100ug

Purification:Protein A+G purification

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Mouse

Clonality:monoclonal

Clone ID:8A11

Isotype:IgG2a

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:Forms a voltage-independent potassium channel that is activated by intracellular calcium(PubMed:26148990). Activation is followed by membrane hyperpolarization which promotes calcium influx. Required for maximal calcium influx and proliferation during the reactivation of naive T-cells. The channel is blocked by clotrimazole and charybdotoxin but is insensitive to apamin(PubMed:17157250, PubMed:18796614).

Immunogen:potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4

Synonyms:IK1, IKCA1, KCA4, SK4

Observed MW:48 kDa

Uniprot ID:O15554

Reactivity:Human, Mouse, Rat

Tested Application:ELISA, WB

Recommended dilution:WB: 1:500 - 1:2000

Gene ID:3783

Research Area:Neuroscience, Developmental biology