KANK1 Antibody, FITC conjugated - Cat. #: CSB-PA614803LC01HU

SKU: CSB-PA614803LC01HU

Size :50ug

Clone Number:

Aliases:ANKRD 15 antibody; Ankyrin repeat domain 15 antibody; Ankyrin repeat domain containing protein 15 antibody; Ankyrin repeat domain-containing protein 15 antibody; DKFZp451G231 antibody; KANK antibody; KANK1 antibody; KANK1_HUMAN antibody; KIAA0172 antibody; Kidney ankyrin repeat containing protein antibody; Kidney ankyrin repeat-containing protein antibody; KN motif and ankyrin repeat domain-containing protein 1 antibody; MGC43128 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q14678

Immunogen:Recombinant Human KN motif and ankyrin repeat domain-containing protein 1 protein (66-255AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:

Background:Involved in the control of cytoskeleton formation by regulating actin polymerization. Inhibits actin fiber formation and cell migration. Inhibits RhoA activity; the function involves phosphorylation through PI3K/Akt signaling and may depend on the competetive interaction with 14-3-3 adapter proteins to sequester them from active complexes. Inhibits the formation of lamellipodia but not of filopodia; the function may depend on the competetive interaction with BAIAP2 to block its association with activated RAC1. Inhibits fibronectin-mediated cell spreading; the function is partially mediated by BAIAP2. Inhibits neurite outgrowth. Involved in the establishment and persistence of cell polarity during directed cell movement in wound healing. In the nucleus, is involved in beta-catenin-dependent activation of transcription. Potential tumor suppressor for renal cell carcinoma.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:FITC

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:KANK1

Research Areas:Cancer;Signal transduction