GeneBio Systems
JAM-A/F11R Monoclonal Antibody
JAM-A/F11R Monoclonal Antibody
SKU:AN200027P
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Storage:This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
Shipping:Ice bag
Exp date:12 months
Category ID_II:Primary Antibodies
Category ID_III:Monoclonal Antibodies
Abbreviation:F11R
Target Synonym:PAM;UNQ;PRO;Platelet Adhesion Molecule;Junctional Adhesion Molecule;F11R;CD321;JAM;JAM1;JAMA;JCAM;KAT;PAM-1;JAM-1;JAM-A;Junctional Adhesion Molecule 1;Junctional Adhesion Molecule A;Platelet Adhesion Molecule 1;Platelet F11 Receptor;UNQ264;PRO301;JAM;JAM-A;F11R;CD 321;CD321 antigen;ESTM33;F11 receptor;homolog of;JAM 1;JAM A;Jcam1;Junction adhesion molecule;Junction adhesion molecule 1;Ly106;mouse;PAM 1;PAM1
Research Areas:Cardiovascular;Signal Transduction
Conjugation:Unconjugated
Host:Mouse
Species reactivity:Human
Application:FCM;ICC/IF
Isotype:IgG1
Clonality:Monoclonal
Clone NO.:6G12
UNIProt ID:Q9Y624
Accession:
Background:Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as (1) a receptor for reovirus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor. Multiple 2' alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established.
Concentration:1 mg/mL
Immunogen:Recombinant Human JAM-A / F11R / CD321 protein
Buffer:0.2 μm filtered solution in PBS
Purification method:Protein A
Dilution:ICC/IF 1:20-1:100;FCM 1:25-1:100;
Calculated MW:
ObservedMW:
