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GeneBio Systems

JAM-A/F11R Monoclonal Antibody

JAM-A/F11R Monoclonal Antibody

SKU:AN200027P

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Storage:This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Monoclonal Antibodies

Abbreviation:F11R

Target Synonym:PAM;UNQ;PRO;Platelet Adhesion Molecule;Junctional Adhesion Molecule;F11R;CD321;JAM;JAM1;JAMA;JCAM;KAT;PAM-1;JAM-1;JAM-A;Junctional Adhesion Molecule 1;Junctional Adhesion Molecule A;Platelet Adhesion Molecule 1;Platelet F11 Receptor;UNQ264;PRO301;JAM;JAM-A;F11R;CD 321;CD321 antigen;ESTM33;F11 receptor;homolog of;JAM 1;JAM A;Jcam1;Junction adhesion molecule;Junction adhesion molecule 1;Ly106;mouse;PAM 1;PAM1

Research Areas:Cardiovascular;Signal Transduction

Conjugation:Unconjugated

Host:Mouse

Species reactivity:Human

Application:FCM;ICC/IF

Isotype:IgG1

Clonality:Monoclonal

Clone NO.:6G12

UNIProt ID:Q9Y624

Accession:

Background:Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as (1) a receptor for reovirus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor. Multiple 2' alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established.

Concentration:1 mg/mL

Immunogen:Recombinant Human JAM-A / F11R / CD321 protein

Buffer:0.2 μm filtered solution in PBS

Purification method:Protein A

Dilution:ICC/IF 1:20-1:100;FCM 1:25-1:100;

Calculated MW:

ObservedMW:

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