ITM2C antibody , Cat. # FNab04419

SKU: FNab04419

Size:100ug

Purification:Protein A+G purification

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Mouse

Clonality:monoclonal

Clone ID:5D9

Isotype:IgG2a

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:Negative regulator of beta amyloid peptide production. May inhibit the processing of APP by blocking its access to alpha-and beta-secretase. Binding to the beta-secretase-cleaved APP C-terminal fragment is negligible, suggesting that ITM2C is a poor gamma-secretase cleavage inhibitor. May play a role in TNF-induced cell death and neuronal differentiation(By similarity).

Immunogen:integral membrane protein 2C

Synonyms:BRI3

Observed MW:35 kDa

Uniprot ID:Q9NQX7

Reactivity:Human

Tested Application:ELISA, WB, IF

Recommended dilution:WB: 1:500-1:1000; IF: 1:20-1:200

Gene ID:81618

Research Area:Neuroscience