ITM2B Polyclonal Antibody

SKU: E-AB-52586

Size::120μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Polyclonal Antibodies

Abbreviation:ITM2B

Target Synonym:ABRI;ABri/ADan amyloid peptide;BRI 2;BRI;BRI2;BRICD 2B;BRICD2B;BRICHOS domain containing 2B;E25B;E3 16;E3-16;FBD;imBRI2;Immature BRI2;Integral membrane protein 2B;ITM 2B;ITM2B;ITM2B;Protein E25B;RDGCA;Transmembrane protein BRI

Research Areas:Neuroscience

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:WB

Isotype:IgG

Clonality:Polyclonal

Clone NO.:

UNIProt ID:Q9Y287

Accession:

Background:Amyloid precursor proteins are processed by beta-secretase and gamma-secretase to produce beta-amyloid peptides which form the characteristic plaques of Alzheimer disease. This gene encodes a transmembrane protein which is processed at the C-terminus by furin or furin-like proteases to produce a small secreted peptide which inhibits the deposition of beta-amyloid. Mutations which result in extension of the C-terminal end of the encoded protein, thereby increasing the size of the secreted peptide, are associated with two neurogenerative diseases, familial British dementia and familial Danish dementia.

Concentration:0.96 mg/mL

Immunogen:Fusion protein of human ITM2B

Buffer:PBS with 0.05% NaN3 and 40% Glycerol,pH7.4

Purification method:Antigen affinity purification

Dilution:WB 1:500-1:2000

Calculated MW:30 kDa

ObservedMW:Refer to figures