IRF3 Monoclonal Antibody

SKU: BT-MCA4335

Size:100μL

Background:This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. The protein plays an important role in the innate immune response against DNA and RNA viruses. Mutations in this gene are associated with Encephalopathy, acute, infection-induced, herpes-specific, 7.

Research_area:Immunology

Target_protein:IRF3

applications:WB, IHC, FCM

Reactivity:Human, Mouse, Rat

Clonality:Monoclonal

Clone ID:5G3E2

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:IRF3

Immunogen:Purified recombinant fragment of human IRF3 (AA: 1-150) expressed in HEK293-6e cells supernatant.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Purified antibody in PBS with 0.05% sodium azide

Concentration:

Molecular weight(Da):47.2kDa

UniProt accession:Q14653

Synonyms:IIAE7

GeneID:3661