IP3 Receptor (Phospho Tyr353) rabbit pAb

SKU: ES20180

Size: 100μL

Source:Rabbit

Applications:WB;IHC

Reactivity:Human;Mouse;Rat

Dilution:WB 1:500-2000;IHC-p 1:50-300

Immunogen:Synthesized peptide derived from human IP3 Receptor (Phospho Tyr353)

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:1 mg/ml

Observed_band(KD):320kD

Human_gene_id:3708

Human_swiss_prot_no:Q14643

Subcellular_location:Endoplasmic reticulum membrane ; Multi-pass membrane protein . Cytoplasmic vesicle, secretory vesicle membrane ; Multi-pass membrane protein . Cytoplasm, perinuclear region . Endoplasmic reticulum and secretory granules (By similarity). .

Other_name:Inositol 1,4,5-trisphosphate receptor type 1 (IP3 receptor isoform 1;IP3R 1;InsP3R1;Type 1 inositol 1,4,5-trisphosphate receptor;Type 1 InsP3 receptor)

Background:This gene encodes an intracellular receptor for inositol 1,4,5-trisphosphate. Upon stimulation by inositol 1,4,5-trisphosphate, this receptor mediates calcium release from the endoplasmic reticulum. Mutations in this gene cause spinocerebellar ataxia type 15, a disease associated with an heterogeneous group of cerebellar disorders. Multiple transcript variants have been identified for this gene. [provided by RefSeq, Nov 2009],