InVivoMAb Anti-Mouse CD198/CCR8 Antibody (Iv0255)

SKU: MW444010

Size:100ug

Description:Iv0255 is an antibody that recognizes mouse CCR8, a chemokine receptor involved in recruiting and regulating immunosuppressive T cells in the tumor microenvironment. Iv0255 shows clear dose-dependent anti-tumor activity across multiple mouse models. In CD34 humanized mice, intravenous Iv0255 effectively inhibited the growth of HCC827 human lung cancer xenografts. In syngeneic models, intraperitoneal Iv0255 similarly suppressed tumor growth in both LLC lung cancer and H22 liver cancer. Higher doses consistently produced stronger tumor-volume inhibition.

Host species:Mouse

Species reactivity:Mouse

Form:Liquid

Storage buffer:0.01M PBS, pH 7.4.

Purity:>95% as determined by SDS-PAGE.

Clonality:Monoclonal

Isotype:IgG2a, kappa

Applications:ELISA, Neutralization

Target:C-C chemokine receptor type 8, C-C CKR-8, CC-CKR-8, CCR-8, CDw198, Ccr8, Cmkbr8, Ter1

Purification:Protein A/G purified from cell culture supernatant.

Endotoxin level:Please contact us for this information.

Accession:P56484

Stability and Storage:Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID:Iv0255

Product Usage Information:

Predicted molecular weight:

Note:For research use only. Not suitable for clinical or therapeutic use.