InVivoMAb Anti-Human CXCL12/SDF-1 (Iv0090)

SKU: HW376010

Size:100ug

Description:Iv0090 is a human IgG monoclonal antibody targeting CXCL12α, β, and γ. It blocks CXCL12 binding to CXCR4 and CXCR7 and inhibits CXCL12-driven cell migration in vitro. In vivo, Iv0090 significantly inhibits tumor growth and metastasis, reduces arthritis severity in mouse CIA models, and decreases laser-induced choroidal neovascularization by 50%.

Host species:Human

Species reactivity:Human

Form:Liquid

Storage buffer:0.01M PBS, pH 7.4.

Purity:>95% as determined by SDS-PAGE.

Clonality:Monoclonal

Isotype:IgG1, kappa

Applications:ELISA, Neutralization

Target:Intercrine reduced in hepatomas, hSDF-1, Stromal cell-derived factor 1, SDF-1, Pre-B cell growth-stimulating factor, SDF1, SDF1A, C-X-C motif chemokine 12, SDF1B, CXCL12, IRH, PBSF, hIRH

Purification:Protein A/G purified from cell culture supernatant.

Endotoxin level:Please contact us for this information.

Accession:P48061

Stability and Storage:Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID:Iv0090

Product Usage Information:

Predicted molecular weight:

Note:For research use only. Not suitable for clinical or therapeutic use.