IL7 Antibody - Cat. #: CSB-PA011669KA01HU

SKU: CSB-PA011669KA01HU

Size :100ul

Clone Number:

Aliases:IL 7 antibody; IL-7 antibody; Il7 antibody; IL7_HUMAN antibody; Interleukin 7 antibody; Interleukin-7 antibody; LP-1 antibody; Lymphopoietin 1 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P13232

Immunogen:Recombinant protein of Human IL7

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, WB, IHC; WB:1:500-1:2000, IHC:1:50-1:200

Background:IL-7 plays a key role in lymphopoiesis and lymphoid homeostasis. Stromal and epithelial cells within the bone marrow and thymus produce IL-7. The primary targets of IL-7 are T cells, B cells, and dendritic cells. IL-7 is crucial for T cell development, the importance of which is underscored by the lack of T cells in both mice and humans that are deficient in IL-7/IL-7R signaling. While IL-7 appears to be required for B cell development in mice, the role of IL-7 in human B cell development is unclear. In addition to its effects on T cell lymphopoiesis, IL-7 promotes the maintenance and survival of naïve and memory ?? T cells, as well as ?? T cells. The IL-7 receptor is a heterodimer of the common ? chain, ?c, and the IL-7-specific IL-7R?. IL-7 activates PI3K/Akt, Jak1/2, and Stat1, 3, and 5.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Affinity purification

Conjugate:Non-conjugated

Buffer:Store at -20°C or -80°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:IL7

Research Areas:Immunology