IL1 Beta antibody , Cat. # FNab04210

SKU: FNab04210

Size:100ug

Purification:Protein G purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Mouse

Clonality:monoclonal

Clone ID:9G5

Isotype:IgG1

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2.

Immunogen:interleukin 1, beta

Synonyms:IL1 beta, Catabolin, IL 1, IL 1 beta, IL1 BETA, IL1B, IL1beta, IL1F2, IL-1?, Interleukin 1 beta, interleukin 1, beta

Observed MW:35kDa

Uniprot ID:P01584

Reactivity:Human

Tested Application:ELISA, IHC, WB

Recommended dilution:WB: 1:1000-1:4000; IHC: 1:50-1:500

Gene ID:3553

Research Area:Neuroscience, Immunology, Cardiovascular, Signal Transduction