IkB alpha antibody , Cat. # FNab04197

SKU: FNab04197

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease.

Immunogen:nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha

Synonyms:I kappa B alpha, IkappaBalpha, IkB alpha, IKBA, Ik?-?, MAD 3, MAD3, NF kappa B inhibitor alpha, NFKBI, NFKBIA

Observed MW:39 kDa

Uniprot ID:P25963

Reactivity:Human, Mouse, Rat

Tested Application:ELISA, WB, IHC, IP

Recommended dilution:WB: 1:500-1:2000; IP: 1:500-1:2000; IHC: 1:50-1:500

Gene ID:4792

Research Area:Epigenetics, Signal Transduction, Metabolism, Cardiovascular, Immunology