ICAM-1 antibody , Cat. # FNab04103

SKU: FNab04103

Size:100ug

Purification:Protein A+G purification

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Mouse

Clonality:monoclonal

Clone ID:7F11

Isotype:IgG1

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:ICAM-1 (CD54) is a 90-kDa transmembrane glycoprotein of the immunoglobulin superfamily and is critical for the firm attachment and transmigration of leukocytes out of blood vessels and into tissues (PMID: 19307690). ICAM-1 is expressed by several cell types, typically on endothelial cells and cells of the immune system, and its expression can be up-regulated by various stimuli, including TNF-?, INF-?, IL-1 and thrombin (PMID: 3086451; 9694714; 15979056). It is a ligand for LFA-1 and Mac-1, serves as a receptor for rhinovirus, and is one of several receptors used by Plasmodium falciparum (PMID: 2566624; 2538244; 2475784).

Immunogen:intercellular adhesion molecule 1

Synonyms:BB2, CD54, ICAM 1, ICAM1, ICAM-1, P3.58

Observed MW:85-95 kDa

Uniprot ID:P05362

Reactivity:Human

Tested Application:ELISA, IHC, WB, FC

Recommended dilution:WB: 1:1000-1:4000; IHC: 1:50-1:500

Gene ID:3383

Research Area:Stem Cells, Immunology, Cardiovascular