Human Visfatin, VISFATIN ELISA Kit

SKU: E0025Hu

Size:96 Tests-1 Kit

Background:Catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, an intermediate in the biosynthesis of NAD. It is the rate limiting component in the mammalian NAD biosynthesis pathway. The secreted form behaves both as a cytokine with immunomodulating properties and an adipokine with anti-diabetic properties, it has no enzymatic activity, partly because of lack of activation by ATP, which has a low level in extracellular space and plasma. Plays a role in the modulation of circadian clock function. NAMPT-dependent oscillatory production of NAD regulates oscillation of clock target gene expression by releasing the core clock component: CLOCK-ARNTL/BMAL1 heterodimer from NAD-dependent SIRT1-mediated suppression (By similarity).

Research_area:Metabolism

Applications:ELISA

Target_protein:VISFATIN

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.23ng/ml

Detection range:0.5-100ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Visfatin

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P43490

MASS(Da):55,521

GeneID:10135

Synonyms:NAmPRTase;Nampt;Nicotinamide phosphoribosyltransferase;Pre-B cell-enhancing factor;Pre-B-cell colony-enhancing factor 1;VISFATIN

Gene names:VISFATIN

Standard solution:128ng/ml