Human Ubiquitin Conjugating Enzyme E2 C,UBE2C ELISA KIT

SKU: E7395Hu

Size:96 Tests-1 Kit

Background:Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-11'- and 'Lys-48'-linked polyubiquitination. Acts as an essential factor of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated ubiquitin ligase that controls progression through mitosis. Acts by initiating 'Lys-11'-linked polyubiquitin chains on APC/C substrates, leading to the degradation of APC/C substrates by the proteasome and promoting mitotic exit. {ECO:0000269|PubMed:15558010, ECO:0000269|PubMed:18485873, ECO:0000269|PubMed:19820702, ECO:0000269|PubMed:19822757, ECO:0000269|PubMed:20061386, ECO:0000269|PubMed:27259151}.

Research_area:

Applications:ELISA

Target_protein:UBE2C

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.032ng/ml

Detection range:0.05-30ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Ubiquitin Conjugating Enzyme E2 C

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:O00762

MASS(Da):19652

GeneID:11065

Synonyms:UBE2C UBCH10

Gene names:UBE2C

Standard solution:32ng/ml