Human U5 Small Nuclear Ribonucleoprotein 200 kDa Helicase, SNRNP200 ELISA Kit

SKU: E6370Hu

Size:96 Tests-1 Kit

Background:Plays role in pre-mRNA splicing as core component of precatalytic, catalytic and postcatalytic spliceosomal complexes (PubMed:28502770, PubMed:28781166, PubMed:29361316, PubMed:30315277, PubMed:29360106, PubMed:29301961, PubMed:30728453, PubMed:30705154). Involved in spliceosome assembly, activation and disassembly. Mediates changes in the dynamic network of RNA-RNA interactions in the spliceosome. Catalyzes the ATP-dependent unwinding of U4/U6 RNA duplices, an essential step in the assembly of a catalytically active spliceosome.

Research_area:Others

Applications:ELISA

Target_protein:SNRNP200

Reactivity:Human

Assay type:Sandwich

Sensitivity:7.46ng/L

Detection range:15-3000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:U5 small nuclear ribonucleoprotein 200 kDa helicase

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:O75643

MASS(Da):244,508

GeneID:23020

Synonyms:Activating signal cointegrator 1 complex subunit 3-like 1;ASCC3L1;BRR2;BRR2 homolog;HELIC2;RP33;SNRNP200;U5 small nuclear ribonucleoprotein 200 kDa helicase;U5 snRNP-specific 200 kDa protein;U5-200KD

Gene names:SNRNP200

Standard solution:3200ng/L