Human Tubulin Beta-3 Chain, TUBB3 ELISA Kit

SKU: E6334Hu

Size:96 Tests-1 Kit

Background:Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. TUBB3 plays a critical role in proper axon guidance and mantainance. Binding of NTN1/Netrin-1 to its receptor UNC5C might cause dissociation of UNC5C from polymerized TUBB3 in microtubules and thereby lead to increased microtubule dynamics and axon repulsion (PubMed: 28483977). Plays a role in dorsal root ganglion axon projection towards the spinal cord (PubMed: 28483977).

Research_area:Signal Transduction

Applications:ELISA

Target_protein:TUBB3

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.146ng/ml

Detection range:0.3-90ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Tubulin Beta-3 Chain

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q13509

MASS(Da):50,433

GeneID:10381

Synonyms:TUBB 3;TUBB3;Tubulin beta-3 chain;Tubulin beta-4 chain;Tubulin beta-III

Gene names:TUBB3

Standard solution:96ng/ml