Human TIMP-3 ELISA Kit PicoKine®

SKU: EK0523

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: TIMP3

Specificity: Natural and recombinant human TIMP-3

Background: The tissue inhibitors of metalloproteinases (TIMPs) are natural inhibitors of the matrix metalloproteinases, a group of zinc-binding endopeptidases involved in the degradation of the extracellular matrix. The TIMP3 gene is expressed in many tissues, with highest expression in the placenta. TIMP3 encodes a potent angiogenesis inhibitor and is mutated in Sorsby fundus dystrophy, a macular degenerative disease with submacular choroidal neovascularization. TIMP3 gene is mapped to 22q12.1-q13.2. Mutations in TIMP3 cause the autosomal dominant disorder Sorsby's fundus dystrophy (SFD).

Immunogen: Expression system for standard: NS0; Immunogen sequence: C24-P211

Clonality:

Contents:

Purification:

Reconstitution:

Reference:

Uniprot ID: P35625

Host:

Concentration:

Conjugate:

Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

Isotype:

Phospho_site:

Clone Number:

Observed Molecular Weight:

Calculated Molecular Weight:

Gene ID: 7078

Protein Name: Metalloproteinase inhibitor 3

Gene Full Name: TIMP metallopeptidase inhibitor 3

Synonyms: HSMRK222; K222; K222TA2; Metalloproteinase inhibitor 3; Protein MIG 5; SFD; Timp 3; TIMP3; TIMP-3