Human Tetraspanin 30Cluster of Differentiation 63,CD63 ELISA KIT

SKU: E7406Hu

Size:96 Tests-1 Kit

Background:Functions as cell surface receptor for TIMP1 and plays a role in the activation of cellular signaling cascades. Plays a role in the activation of ITGB1 and integrin signaling, leading to the activation of AKT, FAK/PTK2 and MAP kinases. Promotes cell survival, reorganization of the actin cytoskeleton, cell adhesion, spreading and migration, via its role in the activation of AKT and FAK/PTK2. Plays a role in VEGFA signaling via its role in regulating the internalization of KDR/VEGFR2. Plays a role in intracellular vesicular transport processes, and is required for normal trafficking of the PMEL luminal domain that is essential for the development and maturation of melanocytes. Plays a role in the adhesion of leukocytes onto endothelial cells via its role in the regulation of SELP trafficking. May play a role in mast cell degranulation in response to Ms4a2/FceRI stimulation, but not in mast cell degranulation in response to other stimuli. {ECO:0000269|PubMed:16917503, ECO:0000269|PubMed:21803846, ECO:0000269|PubMed:21962903, ECO:0000269|PubMed:23632027, ECO:0000269|PubMed:24635319}.

Research_area:

Applications:ELISA

Target_protein:CD63

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.12ng/ml

Detection range:0.2-70ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Tetraspanin 30Cluster of Differentiation 63

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P08962

MASS(Da):25637

GeneID:967

Synonyms:CD63 MLA1 TSPAN30

Gene names:CD63

Standard solution:80ng/ml