Human Solute Carrier Family 12 Member 5, SLC12A5 ELISA Kit

SKU: E6522Hu

Size:96 Tests-1 Kit

Background:Mediates electroneutral potassium-chloride cotransport in mature neurons and is required for neuronal Cl- homeostasis. As major extruder of intracellular chloride, it establishes the low neuronal Cl- levels required for chloride influx after binding of GABA-A and glycine to their receptors, with subsequent hyperpolarization and neuronal inhibition (By similarity). Involved in the regulation of dendritic spine formation and maturation (PubMed:24668262).

Research_area:Neuroscience

Applications:ELISA

Target_protein:SLC12A5

Reactivity:Human

Assay type:Sandwich

Sensitivity:6.97ng/L

Detection range:15-3000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Solute carrier family 12 member 5

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q9H2X9

MASS(Da):126,184

GeneID:57468

Synonyms:DEE34;EIEE34;EIG14;Electroneutral potassium-chloride cotransporter 2;hKCC2;KCC2;K-Cl cotransporter 2;Neuronal K-Cl cotransporter;SLC12A5;Solute carrier family 12 member 5

Gene names:SLC12A5

Standard solution:3200ng/L