Human Soluble Interleukin-17 Receptor, SIL-17R ELISA Kit

SKU: E4688Hu

Size:96 Tests-1 Kit

Background:Feedback inhibitor of fibroblast growth factor mediated Ras-MAPK signaling and ERK activation (PubMed: 12958313, PubMed: 12807873). Regulates the nuclear ERK signaling pathway by spatially blocking nuclear translocation of activated ERK without inhibiting cytoplasmic phosphorylation of ERK (PubMed: 15239952). Mediates JNK activation and may be involved in apoptosis (By similarity). May inhibit FGF-induced FGFR1 tyrosine phosphorylation (By similarity). Might have a role in the early stages of fate specification of GnRH-secreting neurons (By similarity). Inhibits TGFB-induced epithelial-to-mesenchymal transition in lens epithelial cells (By similarity).

Research_area:Others

Applications:ELISA

Target_protein:IL17RD

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.017ng/ml

Detection range:0.05-20ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Soluble Interleukin-17 Receptor

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q8NFM7

MASS(Da):82,411

GeneID:54756

Synonyms:hSef;IL 17RD;IL-17 receptor D;IL17RD;IL-17RD;IL17Rhom;Interleukin-17 receptor D;Interleukin-17 receptor-like protein;Sef homolog;

Gene names:IL17RD

Standard solution:24ng/ml