Human Short Branched Chain Specific Acyl-CoA Dehydrogenase, ACADSB ELISA Kit

SKU: E6171Hu

Size:96 Tests-1 Kit

Background:Short and branched chain specific acyl-CoA dehydrogenase that catalyzes the removal of one hydrogen from C-2 and C-3 of the fatty acyl-CoA thioester, resulting in the formation of trans-2-enoyl-CoA (PubMed:7698750, PubMed:11013134, PubMed:21430231, PubMed:10832746). Among the different mitochondrial acyl-CoA dehydrogenases, acts specifically on short and branched chain acyl-CoA derivatives such as (S)-2-methylbutyryl-CoA as well as short straight chain acyl-CoAs such as butyryl-CoA (PubMed:7698750, PubMed:11013134, PubMed:21430231, PubMed:10832746). Plays an important role in the metabolism of L-isoleucine by catalyzing the dehydrogenation of 2-methylbutyryl-CoA, one of the steps of the L-isoleucine catabolic pathway (PubMed:11013134, PubMed:10832746). Can also act on valproyl-CoA, a metabolite of valproic acid, an antiepileptic drug (PubMed:8660691).

Research_area:Others

Applications:ELISA

Target_protein:ACADSB

Reactivity:Human

Assay type:Sandwich

Sensitivity:9.63ng/L

Detection range:20-4500ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Short/branched chain specific acyl-CoA dehydrogenase

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P45954

MASS(Da):47,485

GeneID:36

Synonyms:2-MEBCAD;2-methyl branched chain acyl-CoA dehydrogenase;2-methylbutyryl-CoA dehydrogenase;2-methylbutyryl-coenzyme A dehydrogenase;ACAD7;ACADSB;SBCAD;Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial

Gene names:ACADSB

Standard solution:4800ng/L