Human Serine;threonine-protein phosphatase PGAM5, mitochondrial,PGAM5 ELISA KIT

SKU: E7240Hu

Size:96 Tests-1 Kit

Background:Displays phosphatase activity for serine/threonine residues, and, dephosphorylates and activates MAP3K5 kinase. Has apparently no phosphoglycerate mutase activity. May be regulator of mitochondrial dynamics. Substrate for a KEAP1-dependent ubiquitin ligase complex. Contributes to the repression of NFE2L2-dependent gene expression. Acts as a central mediator for programmed necrosis induced by TNF, by reactive oxygen species and by calcium ionophore. {ECO:0000269|PubMed:18387606, ECO:0000269|PubMed:19590015, ECO:0000269|PubMed:22265414}.

Research_area:

Applications:ELISA

Target_protein:PGAM5

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.25ng/ml

Detection range:0.5-32ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q96HS1

MASS(Da):32004

GeneID:192111

Synonyms:PGAM5

Gene names:PGAM5

Standard solution:64ng/ml