Human Semaphorin 4D, SEMA4D ELISA Kit

SKU: E1566Hu

Size:96 Tests-1 Kit

Background:Cell surface receptor for PLXNB1 and PLXNB2 that plays an important role in cell-cell signaling (PubMed: 20877282). Regulates GABAergic synapse development (By similarity). Promotes the development of inhibitory synapses in a PLXNB1-dependent manner (By similarity). Modulates the complexity and arborization of developing neurites in hippocampal neurons by activating PLXNB1 and interaction with PLXNB1 mediates activation of RHOA (PubMed: 19788569). Promotes the migration of cerebellar granule cells (PubMed: 16055703). Plays a role in the immune system; induces B-cells to aggregate and improves their viability (in vitro) (PubMed: 8876214). Induces endothelial cell migration through the activation of PTK2B/PYK2, SRC, and the phosphatidylinositol 3-kinase-AKT pathway (PubMed: 16055703).

Research_area:Neuroscience

Applications:ELISA

Target_protein:SEMA4D

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.1ng/ml

Detection range:0.2-60ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Semaphorin 4D

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q92854

MASS(Da):96,150

GeneID:10507

Synonyms:A8;BB18;CD antigen CD100;GR3;SEMA4D;Semaphorin-4D

Gene names:SEMA4D

Standard solution:64ng/ml