Human Secreted Frizzled Related Protein 1, SFRP1 ELISA Kit

SKU: E2326Hu

Size:96 Tests-1 Kit

Background:Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP1 decreases intracellular beta-catenin levels (By similarity). Has antiproliferative effects on vascular cells, in vitro and in vivo, and can induce, in vivo, an angiogenic response. In vascular cell cycle, delays the G1 phase and entry into the S phase (By similarity). In kidney development, inhibits tubule formation and bud growth in metanephroi (By similarity). Inhibits WNT1/WNT4-mediated TCF-dependent transcription.

Research_area:Cell Biology

Applications:ELISA

Target_protein:SFRP1

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.46ng/L

Detection range:1-400ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Secreted Frizzled Related Protein 1

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q8N474

MASS(Da):35,386

GeneID:6422

Synonyms:FRP-1;SARP-2;Secreted apoptosis-related protein 2;Secreted frizzled-related protein 1;SFRP 1;SFRP1;sFRP-1

Gene names:SFRP1

Standard solution:480ng/L