Human SAM and SH3 domain-containing 1,SASH1 ELISA KIT

SKU: E7464Hu

Size:96 Tests-1 Kit

Background:Is a positive regulator of NF-kappa-B signaling downstream of TLR4 activation. It acts as a scaffold molecule to assemble a molecular complex that includes TRAF6, MAP3K7, CHUK and IKBKB, thereby facilitating NF-kappa-B signaling activation (PubMed:23776175). Regulates TRAF6 and MAP3K7 ubiquitination (PubMed:23776175). Involved in the regulation of cell mobility (PubMed:23333244, PubMed:23776175, PubMed:25315659). Regulates lipolysaccharide (LPS)-induced endothelial cell migration (PubMed:23776175). Is involved in the regulation of skin pigmentation through the control of melanocyte migration in the epidermis (PubMed:23333244). {ECO:0000269|PubMed:23333244, ECO:0000269|PubMed:23776175, ECO:0000269|PubMed:25315659}.

Research_area:

Applications:ELISA

Target_protein:SASH1

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.102ng/ml

Detection range:0.2-60ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:SAM and SH3 domain-containing 1

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:O94885

MASS(Da):136653

GeneID:23328

Synonyms:SASH1 KIAA0790 PEPE1

Gene names:SASH1

Standard solution:64ng/ml