Human Ryanodine Receptor 2, RYR2 ELISA Kit

SKU: E3158Hu

Size:96 Tests-1 Kit

Background:Calcium Channel that mediates the release of Ca(2+) from the sarcoplasmic reticulum into the cytoplasm and thereby plays a key role in triggering cardiac muscle contraction. Aberrant Channel activation can lead to cardiac arrhythmia. In cardiac myocytes, calcium release is triggered by increased Ca(2+) levels due to activation of the L-type calcium Channel CACNA1C. The calcium Channel activity is modulated by formation of heterotetramers with RYR3. Required for cellular calcium ion homeostasis. Required for embryonic heart development.

Research_area:Others

Applications:ELISA

Target_protein:RYR2

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.022ng/ml

Detection range:0.05-20ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Ryanodine Receptor 2

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q92736

MASS(Da):564,567

GeneID:6262

Synonyms:Cardiac muscle ryanodine receptor;Cardiac muscle ryanodine receptor-calcium release Channel;hRYR-2;Ryanodine receptor 2;RYR 2;RYR2;RYR-2;Type 2 ryanodine receptor

Gene names:RYR2

Standard solution:24ng/ml