Human Relaxin-3/RLN3 ELISA Kit PicoKine®

SKU: EK1407

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: RLN3

Specificity: Natural and recombinant human Relaxin 3

Background: Relaxin-3 is a neuropeptide which is highly conserved in species ranging from flies, fish, rodents and humans. It is a member and ancestral gene of the relaxin family of peptides, which includes the namesake hormone relaxin (designated 'H2 relaxin' in humans) which mediates peripheral actions during pregnancy and which was found to relax the pelvic ligament in guinea pigs almost a century ago. The broad distribution of relaxin-3 fibres/RXFP3 within several key neuronal circuits suggests an ability to modulate a broad range of behaviours. This has been confirmed in a growing number of rodent studies, which demonstrate relaxin-3 is able to modulate arousal, the response to stress, feeding/metabolism and memory; and likely plays a role in the generation/regulation of hippocampal theta rhythm.

Immunogen: Expression system for standard: E.coli; Immunogen sequence: D119-C142 (A) & A27-R53 (B)

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Reconstitution:

Reference:

Uniprot ID: Q8WXF3

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 117579

Protein Name: Relaxin-3

Gene Full Name: relaxin 3

Synonyms: H3; insl7; Insulin like peptide 7; Insulin like peptide INSL7; Prorelaxin H3; relaxin 3; RLN3; RXN3; ZINS4