Human Ras-related protein Rap-1A,RAP1A ELISA KIT

SKU: E7641Hu

Size:96 Tests-1 Kit

Background:Induces morphological reversion of a cell line transformed by a Ras oncogene. Counteracts the mitogenic function of Ras, at least partly because it can interact with Ras GAPs and RAF in a competitive manner. Together with ITGB1BP1, regulates KRIT1 localization to microtubules and membranes. Plays a role in nerve growth factor (NGF)-induced neurite outgrowth. Plays a role in the regulation of embryonic blood vessel formation. Involved in the establishment of basal endothelial barrier function. May be involved in the regulation of the vascular endothelial growth factor receptor KDR expression at endothelial cell-cell junctions. {ECO:0000269|PubMed:17916086, ECO:0000269|PubMed:21840392}.

Research_area:

Applications:ELISA

Target_protein:RAP1A

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.13ng/ml

Detection range:0.25-16ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P62834

MASS(Da):20987

GeneID:5906

Synonyms:RAP1A KREV1

Gene names:RAP1A

Standard solution:32ng/ml