Human Protein-glutamine Gamma-glutamyltransferase E, TGM3 ELISA Kit

SKU: E6022Hu

Size:96 Tests-1 Kit

Background:Catalyzes the calcium-dependent formation of isopeptide cross-links between glutamine and lysine residues in various proteins, as well as the conjugation of polyamines to proteins. Involved in the formation of the cornified envelope (CE), a specialized component consisting of covalent cross-links of proteins beneath the plasma membrane of terminally differentiated keratinocytes. Catalyzes small proline-rich proteins (SPRR1 and SPRR2) and LOR cross-linking to form small interchain oligomers, which are further cross-linked by TGM1 onto the growing CE scaffold (By similarity). In hair follicles, involved in cross-linking structural proteins to hardening the inner root sheath.

Research_area:Others

Applications:ELISA

Target_protein:TGM3

Reactivity:Human

Assay type:Sandwich

Sensitivity:9.93ng/L

Detection range:20-4500ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Protein-Glutamine Gamma-Glutamyltransferase E

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q08188

MASS(Da):76,632

GeneID:7053

Synonyms:Protein-glutamine gamma-glutamyltransferase E;Protein-glutamine gamma-glutamyltransferase E 27 kDa non-catalytic chain;Protein-glutamine gamma-glutamyltransferase E 50 kDa catalytic chain;TG(E;TGase E;TGase-3;TGE;TGM 3;TGM3;Transglutaminase E;Transglutaminase-3

Gene names:TGM3

Standard solution:4800ng/L