Human Nectin-2/CD112 ELISA Kit PicoKine®

SKU: EK1960

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: NECTIN2

Specificity: Natural and recombinant human Nectin-2/CD112

Background: Poliovirus receptor-related 2 (PVRL2), also known as nectin-2 and CD112 (formerly herpesvirus entry mediator B, HVEB), is a human plasma membrane glycoprotein. It is mapped to 19q13.32. This gene encodes a single-pass type I membrane glycoprotein with two Ig-like C2-type domains and an Ig-like V-type domain. This protein is one of the plasma membrane components of adherens junctions. It also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, and it is involved in cell to cell spreading of these viruses. Variations in this gene have been associated with differences in the severity of multiple sclerosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Immunogen: Expression system for standard: NS0; Immunogen sequence: Q32-G360

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Reference:

Uniprot ID: Q92692

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 5819

Protein Name: Nectin-2

Gene Full Name: nectin cell adhesion molecule 2

Synonyms: CD112; Herpes virus entry mediator B; Herpesvirus entry mediator B; HVEB; Nectin-2; PRR2; PVRL2; PVRR2