Human Melanoma-associated Antigen D1, MAGED1 ELISA Kit

SKU: E5656Hu

Size:96 Tests-1 Kit

Background:Involved in the apoptotic response after nerve growth factor (NGF) binding in neuronal cells. Inhibits cell cycle progression, and facilitates NGFR-mediated apoptosis. May act as a regulator of the function of DLX family members. May enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex. Plays a role in the circadian rhythm regulation. May act as RORA co-regulator, modulating the expression of core clock genes such as ARNTL/BMAL1 and NFIL3, induced, or NR1D1, repressed.

Research_area:Others

Applications:ELISA

Target_protein:MAGED1

Reactivity:Human

Assay type:Sandwich

Sensitivity:8.92ng/L

Detection range:20-4500ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Melanoma-Associated Antigen D1

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q9Y5V3

MASS(Da):86,161

GeneID:9500

Synonyms:MAGE tumor antigen CCF;MAGED 1;MAGED1;MAGE-D1 antigen;Melanoma-associated antigen D1;Neurotrophin receptor-interacting MAGE homolog

Gene names:MAGED1

Standard solution:4800ng/L