Human Lymphocyte Activation Gene 3 Protein, LAG3 ELISA Kit

SKU: E5606Hu

Size:96 Tests-1 Kit

Background:Lymphocyte-activation gene 3, also known as LAG-3, is a protein which in humans is encoded by the LAG3 gene. LAG3, which was discovered in 1990 and was designated CD223 (cluster of differentiation 223) after the Seventh Human Leucocyte Differentiation Antigen Workshop in 2000, is a cell surface molecule with diverse biologic effects on T cell function. It is an immune checkpoint receptor and as such is the target of various drug development programs by pharmaceutical companies seeking to develop new treatments for cancer and autoimmune disorders. In soluble form it is also being developed as a cancer drug in its own right.

Research_area:Immunology; Cancer

Applications:ELISA

Target_protein:LAG3

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.025ng/mL

Detection range:0.05-20ng/mL

Sample type:Serum, plasma or other biological fluids

Full product name:Lymphocyte activation gene 3 protein

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P18627

MASS(Da):57,449

GeneID:3902

Synonyms:CD antigen CD223;CD223;FDC;LAG3;LAG-3;Lymphocyte activation gene 3 protein;Secreted lymphocyte activation gene 3 protein

Gene names:LAG3

Standard solution:24ng/mL