Human Long-chain-fatty-acid--CoA ligase 4,ACSL4 ELISA KIT

SKU: E7227Hu

Size:96 Tests-1 Kit

Background:Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoA for both synthesis of cellular lipids, and degradation via beta-oxidation (PubMed:24269233, PubMed:22633490, PubMed:21242590). Preferentially activates arachidonate and eicosapentaenoate as substrates (PubMed:21242590). Preferentially activates 8,9-EET > 14,15-EET > 5,6-EET > 11,12-EET. Modulates glucose-stimulated insulin secretion by regulating the levels of unesterified EETs (By similarity). Modulates prostaglandin E2 secretion (PubMed:21242590). {ECO:0000250|UniProtKB:O35547, ECO:0000269|PubMed:21242590, ECO:0000269|PubMed:22633490, ECO:0000269|PubMed:24269233}.

Research_area:

Applications:ELISA

Target_protein:ACSL4

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.14ng/ml

Detection range:0.25-16ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:O60488

MASS(Da):79188

GeneID:2182

Synonyms:ACSL4 ACS4 FACL4 LACS4

Gene names:ACSL4

Standard solution:32ng/ml