Human Lecithin Retinol Acyltransferase, LRAT ELISA Kit

SKU: E5559Hu

Size:96 Tests-1 Kit

Background:Transfers the acyl group from the sn-1 position of phosphatidylcholine to all-trans retinol, producing all-trans retinyl esters (PubMed:9920938). Retinyl esters are storage forms of vitamin A (Probable). LRAT plays a critical role in vision (Probable). It provides the all-trans retinyl ester substrates for the isomerohydrolase which processes the esters into 11-cis-retinol in the retinal pigment epithelium; due to a membrane-associated alcohol dehydrogenase, 11 cis-retinol is oxidized and converted into 11-cis-retinaldehyde which is the chromophore for rhodopsin and the cone photopigments (Probable). Required for the survival of cone photoreceptors and correct rod photoreceptor cell morphology (By similarity).

Research_area:Others

Applications:ELISA

Target_protein:LRAT

Reactivity:Human

Assay type:Sandwich

Sensitivity:7.06ng/L

Detection range:15-3000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Lecithin retinol acyltransferase

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:O95237

MASS(Da):25,703

GeneID:9227

Synonyms:LCA14;Lecithin retinol acyltransferase;LRAT;Phosphatidylcholine--retinol O-acyltransferase

Gene names:LRAT

Standard solution:3200ng/L