Human Interleukin-31 Receptor Subunit Alpha, IL31RA ELISA Kit

SKU: E5522Hu

Size:96 Tests-1 Kit

Background:Associates with OSMR to form the interleukin-31 receptor which activates STAT3 and to a lower extent STAT1 and STAT5 (PubMed: 11877449, PubMed: 14504285, PubMed: 15627637, PubMed: 15194700). May function in skin immunity (PubMed: 15184896). Mediates IL31-induced itch, probably in a manner dependent on cation Channels TRPA1 and TRPV1 (By similarity). Positively regulates numbers and cycling status of immature subsets of myeloid progenitor cells in bone marrow in vivo and enhances myeloid progenitor cell survival in vitro (By similarity).

Research_area:Immunology

Applications:ELISA

Target_protein:IL31RA

Reactivity:Human

Assay type:Sandwich

Sensitivity:1.34ng/L

Detection range:3-900ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Interleukin-31 Receptor Subunit Alpha

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q8NI17

MASS(Da):82,954

GeneID:133396

Synonyms:Cytokine receptor-like 3;GLM-R;Gp130-like monocyte receptor;Gp130-like receptor;hGLM-R;IL 31;IL-31 receptor subunit alpha;IL-31R subunit alpha;IL31RA;IL-31RA;IL-31R-alpha;Interleukin-31 receptor subunit alpha;ZcytoR17;

Gene names:IL31RA

Standard solution:960ng/L